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最新诊断I型糖尿病患者在快速血糖控制后的
糖尿病神经病变恶液质和急性双侧白内障形成
In patients with Type 1 diabetes mellitus (DM), the development of
complications within the first few years of diagnosis is very unusual
and the development of complications within weeks of commencement
of insulin therapy is exceptional. Diabetic neuropathic cachexia,
unlike the other more common neuropathies associated with diabetes,
is a rare form of peripheral neuropathy characterized by profound
weight loss, painful dysaesthesias over the limbs and trunk with spontaneous
resolution usually occurring within a year. The morphologically distinct
diabetic or metabolic cataract in patients with newly diagnosed Type
1 DM is also a rare complication. We describe the first case of a
young man with newly diagnosed Type 1 DM who developed these two rare
complications within 3 months of diagnosis and insulin therapy commencement.
Rapid development of complications in this patient raises two possibilities,
i.e. a probable link between the pathophysiology of these two complications
following rapid glycaemic control, and a subset of patients with unusual
susceptibility to complications. We re-emphasize the need for vigilant
monitoring of complications in young diabetic patients, even in the
first few years of their disease. In particular, young patients with
visual impairment should be evaluated carefully for evidence of treatable
eye complications. Diabet. Med. 18, 854-857 (2001)
【引自Diabet Med 2001 Oct;18(10):854-7】 |
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