牛海绵状脑病

Encephalopathy, Bovine Spongiform 
牛海绵状脑病是一种可以在牛中传播的海绵状脑病，与脑组织中异常朊病毒蛋白有关。受感染的动物在出现共济失调的症状后又发生兴奋性增加和流涎症状。这种疾病还与感染反刍类动物的羊瘙痒病的分化蛋白有关。这种病症可能传染给人类，在人类中我们称之为变异型或新变异型克雅氏病。

A transmissible spongiform encephalopathy of cattle associated with abnormal prion proteins in the brain. Affected animals develop excitability and salivation followed by ATAXIA. This disorder has been associated with consumption of SCRAPIE infected ruminant derived protein. This condition may be transmitted to humans, where it is referred to as variant or new variant CREUTZFELDT-JAKOB SYNDROME. (Vet Rec 1998 Jul 25;143(41):101-5)
Bovine spongiform encephalopathy: an overview.

牛海绵状脑病：
牛海绵状脑病（BSE），也就是大家都了解的疯牛病，它是一种侵犯牛中枢神经系统的慢性的，变性性疾病。自从1986年在英国首次诊断该病以来，在全世界已经发现了180000个以上的病例。牛海绵状脑病已经对英国的家畜工业造成了非常严重的影响。该病在比利时，丹麦，法国，爱尔兰，卢森堡，列支敦氏登，荷兰，被爱尔兰，葡萄牙和瑞士也有发生。然而，99%的BSE病例都发生在英国。牛海绵状脑病现在在美国还不存在。

Bovine spongiform encephalopathy (BSE), widely known as "mad cow disease," is a chronic, degenerative disease affecting the central nervous system of cattle. Worldwide, there have been more than 180,000 cases since the disease was first diagnosed in 1986 in Great Britain. Bovine spongiform encephalopathy has had a substantial impact on the livestock industry in the United Kingdom. The disease has also been confirmed in native-born cattle in Belgium, Denmark, France, Ireland, Luxembourg, Liechtenstein, The Netherlands, Northern Ireland, Portugal, and Switzerland. However, over 95% of all BSE cases have occurred in the United Kingdom. Bovine spongiform encephalopathy is not known to exist in the United States.