遗传信息、遗传技术及药物研制的发展方向
[引自JAMA 2001 Feb 7;285(5):551-555]
The completion of the first draft of the human genome has provided
an unprecedented opportunity to understand the genetic and molecular
basis of disease. Parallel developments of new biological technologies,
such as transcript profiling, allow scientists to examine almost any
biological system in high molecular resolution. Contemporary drug discovery
research is now focusing on the identification and validation of pharmaceutical
targets in the molecular pathways/systems embedded in this information.
Novel therapeutic interventions are being developed and evaluated as
a result of this research which will be the basis of innovative pharmaceuticals
of the future.
