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The ICU From the Medical Perspective
Donald Chalfin, MD, MS,[1] of Maimonides Medical Center
in Brooklyn, New York, reviewed errors in the ICU from
the medical perspective.
Errors happen often in the medical environment. Approximately
1 of 3 hospitalized patients will suffer from some form
of medical error. These errors are up to 70% preventable;
and specifically, adverse drug errors may be prevented
in more than 40% of cases. If we consider nosocomial
infections a failure to comply with infection control
guidelines, it is worrisome to know that they represent
the fifth highest cause of hospital death. The report
of the Institute of Medicine is also very distressing:
based on 2 reports by Leape and Brennan and colleagues,[2,3]
and after extrapolating the results to the more than
33.6 million admissions to US hospitals in 1997, it
was inferred that at least 44,000 and perhaps as many
as 98,000 patients die in US hospitals each year as
a result of medical errors.
Although there are no clear boundaries between "medical"
and other types of iatrogenic errors, medicine has some
special characteristics. It involves inpatient and outpatient
care, multiple specialty consultants, more adverse drug
events, and occasionally the practice of defensive medicine.
There is a tendency today to move away from the individual
as the center of error prevention and to focus on the
system permitting these errors. The "paternalistic,"
physician-centered system is replaced by system-based
responsibility and patient accountability. What is more
important is the will of the medical community to accept
errors and to work on their prevention instead of denying
or concealing them.
While the term "iatrogenesis" is widely
used to describe medical errors stemming from the physician
(deriving from the Greek word "iatros," meaning
physician), the term "comiogenesis" (meaning
"care or attendance") might be more appropriate
as it implies an organization or system-based standpoint,
like in cases of nosocomial infections.
There are 2 fundamentally different ways of dealing
with medical errors. The first is quality assurance
in which individuals performing the error are identified
and reprimanded. The second is quality improvement in
which the best practice and constant improvement are
promoted on a system level. Quality assurance blames
the individual and may lead to "error-covering"
behavior. In contrast, by focusing on the system, quality
improvement promotes error unveiling and perfection.
System failures have been described by Leape and coworkers.[4]
They analyzed all admissions to 11 medical and surgical
units in 2 tertiary care hospitals over a 6-month period
and found that 7 systems failures accounted for 78%
of the errors. It was stated that all these errors could
have been improved by better information systems.
There are many studies suggesting that a "closed"
ICU system (discussed in detail below) significantly
decreases medical errors and even mortality.[5,6] Pharmacists'
participation in ICU rounds is another simple measure
with a significant impact: Leape and coworkers[7] have
reported a decrease of 66% in adverse drug events when
the pharmacist is present in rounds as a full member
of the ICU team. When the pharmacist was present, 99%
of his recommendations were accepted by physicians.
Dr. Chalfin concluded that in order to reduce the
amount and the seriousness of errors in the hospital,
there should be active surveillance methods, increase
in applications of information technology, better education
and outcomes research, and the application of quality
improvement. It is important to move to a system where
the error is recognized and admitted, not covered. An
efficient system is the one promoting evidence-based
medicine and improvement rather than sanctions.
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